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Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively.
Potent and specific peptide antagonist of bradykinin B2 receptor.
IC50 and Ki of 1.07 nM and 0.798 nM respectively for bradykinin B2 receptor.
For research use only.
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Bradykinin acetate (CAS 6846-03-3) is a peptide agonist targeting G protein-coupled B1 and B2 receptors It is designed to activate bradykinin receptors thereby modulating inflammatory responses vascular tone and endothelial signaling pathways Bradykinin acetate exerts its biological activity primarily through endothelium-dependent release of nitric oxide and prostacyclin leading to vasodilation Receptor activation also triggers non-vascular smooth muscle contraction increases vascular permeability and mediates pain signaling pathways Based on these pharmacological properties Bradykinin acetate holds research potential in studies of inflammation pain mechanisms and endothelial cell signaling
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Linaclotide acetate is a potent and selective guanylate cyclase C agonist, developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. This product is for research use only.
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Vitamin A (all-trans-Retinol) is an endogenous metabolite. It plays a role in various biological processes and is studied in contexts such as human gut microbiota metabolism, cellular effects on fibroblasts and cancer cell lines, and its metabolism in hepatic microsomes.
Endogenous metabolite
Role in human gut microbiota metabolism
Exhibits cellular effects on fibroblasts and carcinoma cell lines
Metabolism involves hepatic microsomes
Studied in relation to high-fat diets and methionine-choline deficient diets
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Medchemexpress, HY-B0717 25g Tocofersolan D-α-Tocopherol polyethylene glycol 1000 succinate;TPGS;Vitamin E-TPGS CAS:9002-96-4 Formula:C35H58O6 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Bazedoxifene acetate (CAS 198481-33-3) is a selective estrogen receptor modulator (SERM) targeting estrogen receptors (ER) It is designed to modulate ER activity thereby regulating estrogen-dependent cellular pathways Bazedoxifene acetate exerts its biological activity primarily through tissue-specific agonism and antagonism of ER In in vitro studies Bazedoxifene acetate demonstrates receptor modulation with reported affinities (Ki) of 26 nM for ER and 99 nM for ER Based on these pharmacological properties Bazedoxifene acetate holds research potential in osteoporosis and bone metabolism studies as well as in investigations of hormone-responsive cellular mechanisms and pancreatic cancer
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